MAVID multiple alignment server
MAVID multiple alignment server
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DOI：
10.1093/nar/gkg623
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发表时间：
2003-07-01
影响因子：
14.9
通讯作者：
Pachter, L
中科院分区：
文献类型：
--
作者：
Bray, N;Pachter, L
MAVID是适用于许多大基因组区域的多重比对程序。MAVID网络服务器允许生物医学研究人员快速获得基因组序列的多重比对，并随后分析保守区域的比对。MAVID已成功用于灵长类等密切相关物种的比对，也用于人类和河豚等较远生物的比对。服务器速度很快，能够在不到一分钟的时间内对齐数百个数据库。多重比对用于构建序列的系统发育树，其随后用作鉴定比对中的保守区域的基础。该服务器可以在http://baboon.math.berkeley.edu/mavid/上访问。
MAVID is a multiple alignment program suitable for many large genomic regions. The MAVID web server allows biomedical researchers to quickly obtain multiple alignments for genomic sequences and to subsequently analyse the alignments for conserved regions. MAVID has been successfully used for the alignment of closely related species such as primates and also for the alignment of more distant organisms such as human and fugu. The server is fast, capable of aligning hundreds of kilobases in less than a minute. The multiple alignment is used to build a phylogenetic tree for the sequences, which is subsequently used as a basis for identifying conserved regions in the alignment. The server can be accessed at http://baboon.math.berkeley.edu/mavid/.