Extraintestinal manifestations and complications in inflammatory bowel diseases.
Extraintestinal manifestations and complications in inflammatory bowel diseases.
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DOI：
10.3748/wjg.v12.i30.4819
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发表时间：
2006-08
影响因子：
4.3
通讯作者：
K. Rothfuss;E. Stange;K. Herrlinger
中科院分区：
文献类型：
--
作者：
K. Rothfuss;E. Stange;K. Herrlinger
克罗恩病（CD）和溃疡性结肠炎（UC）是慢性炎症性肠病（IBD），通常累及胃肠道以外的器官。这些非肠道疾病被称为肠外症状。将炎症性肠病的真正肠外表现与由营养不良、慢性炎症或治疗副作用引起的继发性肠外并发症区分开来可能是困难的。本文综述了炎症性肠病肠外症状的发生频率、临床表现和治疗意义。如果可能的话，肠外表现与肠外并发症相鉴别。特别注意最近描述的受累部位;即血栓栓塞事件、骨质疏松症、肺部受累和中枢神经系统受累。
Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) that often involve organs other than those of the gastrointestinal tract. These nonintestinal affections are termed extraintestinal symptoms. Differentiating the true extraintestinal manifestations of inflammatory bowel diseases from secondary extraintestinal complications, caused by malnutrition, chronic inflammation or side effects of therapy, may be difficult. This review concentrates on frequency, clinical presentation and therapeutic implications of extraintestinal symptoms in inflammatory bowel diseases. If possible, extraintestinal manifestations are differentiated from extraintestinal complications. Special attention is given to the more recently described sites of involvement; i.e. thromboembolic events, osteoporosis, pulmonary involvement and affection of the central nervous system.