Efficient Synthetic Route to Carbopyronine Fluorenscent Dye Intermediate
Efficient Synthetic Route to Carbopyronine Fluorenscent Dye Intermediate
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DOI：
10.1002/cjoc.200990202
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发表时间：
2009-06-01
影响因子：
5.4
通讯作者：
Bai Yinjuan
中科院分区：
文献类型：
--
作者：
Gu Lijun;Yang Bingqin;Bai Yinjuan
描述了一种通过非质子刘易斯酸辅助环化反应高效、高产率地合成2，7-双（二甲氨基）-9，10-二氢-9，9-二甲基蒽的方法。关键步骤是刘易斯酸辅助的环化反应。考察了几种非质子刘易斯酸的环合反应，确定了环合反应的最佳条件为2.5equv.的刘易斯酸在0 ℃下反应6 h，并在室温下反应10 h。
An efficient synthesis of 2,7-bis(dimethylamino)-9,10-dihydro-9,9-dimethylanthracene via a non-protic Lewis acid assisted cyclization reaction in a high yield was described. The key step was a Lewis acid assisted cyclization reaction. Several non-protic Lewis acids were investigated and the optimal condition of cyclization reaction was determined to be 2.5 equiv. of Lewis acid at 0 degrees C for 6 h and at room temperature for 10 h.