CHARACTERIZATION OF INFLUENZA-A VIRUSES ISOLATED FROM TURKEYS IN ENGLAND DURING MARCH-MAY 1979
CHARACTERIZATION OF INFLUENZA-A VIRUSES ISOLATED FROM TURKEYS IN ENGLAND DURING MARCH-MAY 1979
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DOI：
10.1080/03079458108418477
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发表时间：
1981-01-01
期刊：
影响因子：
2.8
通讯作者：
SPACKMAN, D
中科院分区：
文献类型：
--
作者：
ALEXANDER, DJ;SPACKMAN, D
1979年初春，英格兰至少12个地点的火鸡感染了甲型流感病毒。在这些位点中的5个没有分离到病毒，但有4个位点的禽类对Hav1和Hav2抗原亚型的甲型流感病毒有抗体。对分离的8种病毒进行了分型：A/土耳其/英格兰/192-328/79(Hav1 NAV2/3)、A/土耳其/英格兰/192-329/79(Hav1 N1)、A/土耳其/英格兰/199/79(Hav1 NEQ 1)、A/土耳其/英格兰/214/79(Hav1 NEQ 1)、A/土耳其/英格兰/250/79(HSW 1 N1)、A/土耳其/英格兰/262/79(Hav1 NAV2/3)、A/土耳其/英格兰/272/79(Hav1 Neq1)、A/土耳其/英格兰/384/79(HAV2 Nav4)。对6周龄鸡的致病指数测试与野外火鸡的临床症状一致。199、214和272菌株为极强毒力菌株，384菌株为中等毒力菌株，其余菌株为低毒菌株。
During the early spring of 1979 turkeys on at least 12 sites in England became infected with influenza A viruses. On 5 of these sites no virus was isolated but birds were shown to have antibodies to Hav1 (4 sites) and Hav2 antigenic subtypes of influenza A viruses. The 8 viruses isolated were typed: A/turkey/England/192-328/79 (Hav1 Nav2/3), A/turkey/England/192-329/79 (Hav1 N2), A/turkey/England/199/79 (Hav1 Neq 1), A/turkey/England/214/79 (Hav1 Neq 1), A/turkey/England/250/79 (Hsw 1 N1), A/turkey/England/262/79 (Hav1 Nav2/3), A/turkey/England/272/79 (Hav1 Neq1), A/turkey/England/384/79 (Hav 2 Nav4). Pathogenicity index tests in 6-wk-old chickens agreed with the clinical signs seen in turkeys in the field. Three isolates, 199, 214 and 272, were of extremely high virulence, 384 showed intermediate virulence while the other isolates were of low virulence.