Loss of the Bacterial Flagellar Motor Switch Complex upon Cell Lysis.
Loss of the Bacterial Flagellar Motor Switch Complex upon Cell Lysis.
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DOI：
10.1128/mbio.00298-21
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发表时间：
2021-06-29
期刊：
影响因子：
6.4
通讯作者：
Jensen GJ
中科院分区：
文献类型：
--
作者：
Kaplan M;Tocheva EI;Briegel A;Dobro MJ;Chang YW;Subramanian P;McDowall AW;Beeby M;Jensen GJ
The bacterial flagellar motor is a complex macromolecular machine whose function and self-assembly present a fascinating puzzle for structural biologists. Here, we report that in diverse bacterial species, cell lysis leads to loss of the cytoplasmic switch complex and associated ATPase before other components of the motor. This loss may be prevented by the formation of a cytoplasmic vesicle around the complex. These observations suggest a relatively loose association of the switch complex with the rest of the flagellar machinery.
