Disconnection of the amygdala central nucleus and substantia innominata/nucleus basalis disrupts increments in conditioned stimulus processing in rats.
Disconnection of the amygdala central nucleus and substantia innominata/nucleus basalis disrupts increments in conditioned stimulus processing in rats.
复制标题
杏仁核中央核和无名质/基底核的断开会破坏大鼠条件刺激处理的增量。
DOI：
10.1037//0735-7044.113.1.143
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发表时间：
1999
影响因子：
1.9
通讯作者：
Gallagher,M
中科院分区：
文献类型：
--
作者：
Han,JS;Holland,PC;Gallagher,M
大鼠杏仁核中央核（CN）在一个半球和192免疫球蛋白G（192 IgG）-皂草素损伤的胆碱能神经元在对侧无名质/基底核（SI/nBM）神经毒性病变未能显示增强注意力处理的条件刺激（CS）观察到在假手术大鼠时，CS的预测值被改变。这些不对称病变的大鼠的性能是较差的，比一个结构的单侧病变或在同一半球的两个结构的对称病变的大鼠。这些结果暗示CN和SI/nBM之间的连接在CS的增量注意力处理，扩展了以前的研究，已经显示出类似的影响，无论是CN或SI/nBM的双边病变。
Rats with a neurotoxic lesion of the amygdala central nucleus (CN) in one hemisphere and a 192 immunoglobulin G (192IgG)-saporin lesion of cholinergic neurons in the contralateral substantia innominata/nucleus basalis (SI/nBM) failed to show the enhanced attentional processing of a conditioned stimulus (CS) observed in sham-operated rats when that CS's predictive value was altered. Performance of these asymmetrically lesioned rats was poorer than that of rats with a unilateral lesion of either structure or with a symmetrical lesion of both structures in the same hemisphere. These results implicate connections between the CN and SI/nBM in the incremental attentional processing of CSs, extending previous research that has shown similar effects of bilateral lesions of either the CN or the SI/nBM.