An Intracranial Electroencephalography (iEEG) Brain Function Mapping Tool with an Application to Epilepsy Surgery Evaluation.
An Intracranial Electroencephalography (iEEG) Brain Function Mapping Tool with an Application to Epilepsy Surgery Evaluation.
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颅内脑电图 (iEEG) 脑功能绘图工具在癫痫手术评估中的应用
DOI：
10.3389/fninf.2016.00015
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发表时间：
2016
影响因子：
3.5
通讯作者：
Li X
中科院分区：
文献类型：
--
作者：
Wang Y;Yan J;Wen J;Yu T;Li X
对象：在癫痫手术前，颅内脑电图（iEEG）常用于功能定位和致痫灶定位。虽然植入的电极为致痫区切除提供了关键信息，但仍然缺乏用于电极位置配准和脑功能标测（BFM）可视化的方便临床工具。在这项研究中，我们开发了一个BFM工具，它有助于电极位置配准和BFM可视化，并应用于癫痫手术。方法：BFM工具主要利用电极位置配准和基于其他软件预定义的大脑模型的功能映射。此外，可以使用设置面板轻松调整电极节点和标测属性，例如节点大小/颜色、边缘颜色/厚度、标测方法。此外，用户可以手动导入/导出位置和连接数据，以生成数字供进一步应用。语言区定位的临床研究证明了该软件的作用。结果：BFM工具帮助临床医生和研究人员以简单、快速和灵活的方式可视化植入电极和大脑功能。结论：该工具提供了方便的电极配准，易于脑功能可视化，并具有良好的性能。它面向临床，易于部署和使用。BFM工具适用于癫痫和其他临床iEEG应用。
Objects: Before epilepsy surgeries, intracranial electroencephalography (iEEG) is often employed in function mapping and epileptogenic foci localization. Although the implanted electrodes provide crucial information for epileptogenic zone resection, a convenient clinical tool for electrode position registration and Brain Function Mapping (BFM) visualization is still lacking. In this study, we developed a BFM Tool, which facilitates electrode position registration and BFM visualization, with an application to epilepsy surgeries. Methods: The BFM Tool mainly utilizes electrode location registration and function mapping based on pre-defined brain models from other software. In addition, the electrode node and mapping properties, such as the node size/color, edge color/thickness, mapping method, can be adjusted easily using the setting panel. Moreover, users may manually import/export location and connectivity data to generate figures for further application. The role of this software is demonstrated by a clinical study of language area localization. Results: The BFM Tool helps clinical doctors and researchers visualize implanted electrodes and brain functions in an easy, quick and flexible manner. Conclusions: Our tool provides convenient electrode registration, easy brain function visualization, and has good performance. It is clinical-oriented and is easy to deploy and use. The BFM tool is suitable for epilepsy and other clinical iEEG applications.