Investigating Protein Structure and Evolution with SCOP2.
Investigating Protein Structure and Evolution with SCOP2.
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DOI：
10.1002/0471250953.bi0126s49
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发表时间：
2015-03-09
影响因子：
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通讯作者：
Murzin, Alexey G
中科院分区：
文献类型：
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作者：
Andreeva, Antonina;Howorth, Dave;Murzin, Alexey G
SCOP 2是蛋白质结构分类（SCOP）数据库的继承者，根据其结构和进化关系组织已知结构的蛋白质。它旨在为蛋白质分类提供更先进的框架。SCOP 2分类是根据有向无环图来描述的，其中每个节点定义了由蛋白质结构和序列区域表示的特定类型的关系。SCOP 2数据可通过SCOP 2-Browser和SCOP 2-Graph访问。该协议单元描述了探索和调查SCOP 2进化和结构分组的不同方法。
SCOP2 is a successor to the Structural Classification of Proteins (SCOP) database that organizes proteins of known structure according to their structural and evolutionary relationships. It was designed to provide a more advanced framework for the classification of proteins. The SCOP2 classification is described in terms of a directed acyclic graph in which each node defines a relationship of particular type that is represented by a region of protein structure and sequence. The SCOP2 data are accessible via SCOP2-Browser and SCOP2-Graph. This protocol unit describes different ways to explore and investigate the SCOP2 evolutionary and structural groupings.