CINE MR IMAGING - POTENTIAL FOR THE EVALUATION OF CARDIOVASCULAR FUNCTION
CINE MR IMAGING - POTENTIAL FOR THE EVALUATION OF CARDIOVASCULAR FUNCTION
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DOI：
10.2214/ajr.148.2.239
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发表时间：
1987-02-01
影响因子：
5
通讯作者：
HIGGINS, CB
中科院分区：
文献类型：
--
作者：
SECHTEM, U;PFLUGFELDER, PW;HIGGINS, CB
磁共振成像在确定各种心脏异常的心脏解剖方面是有价值的。然而，通过这种技术评估心功能受到成像时间长和时间分辨率低的限制。新的，最近描述的脉冲序列大大缩短了成像时间，提高了时间分辨率。本文报告了我们在心脏电影磁共振成像方面的早期经验，这是一种使用低翻转角度和梯度回忆回声的稳态（GRASS）梯度回忆采集技术。36名受试者（14名正常志愿者和22名患有冠状动脉或瓣膜性心脏病的患者）获得图像，并在电影成像模式下显示以评估心功能。采集10至12个水平，覆盖整个心脏，每个水平最多24个时间帧，最大成像时间仅为30分钟。由于收缩期和舒张期很容易识别，血液和周围结构的对比很好，因此很容易看到收缩期壁增厚、壁运动和心脏瓣膜的运动。心肌梗死区域清晰可见，特征是没有收缩壁增厚和/或舒张壁变薄。湍流引起血流中的信号丢失，血流中的信号强度通常高于心肌。因此，可以检测到瓣膜反流、瓣膜狭窄和瓣膜下狭窄的湍流血流。磁共振成像是一种很有前途的评价心肌和瓣膜功能的新技术。
MR imaging is valuable in defining cardiac anatomy in a variety of cardiac abnormalities. However, evaluation of cardiac function by this technique has been limited by long imaging times and low temporal resolution. New, recently described pulse sequences shorten imaging time considerably and improve temporal resolution. This paper reports our early experience with cine MR imaging of the heart, a technique of gradient-recalled acquisition in the steady state (GRASS) that uses low flip angles and gradient-recalled echoes. Images were obtained in 36 subjects (14 normal volunteers and 22 patients with coronary artery or valvular heart disease) and displayed in a cinegraphic mode for assessment of cardiac function. The acquisition of 10 to 12 levels, covering the whole heart with up to 24 time frames per level, required a maximum imaging time of only 30 min. Because systole and diastole were readily identified, and the contrast between blood and surrounding structures was excellent, systolic wall thickening, wall motion, and motion of the cardiac valves were visualized easily. Regions of myocardial infarcts were clearly visible and characterized by lack of systolic wall thickening and/or diastolic wall thinning. Turbulence caused signal loss within the flowing blood, which usually had higher signal intensity than myocardium. Therefore, turbulent blood flow in valvular regurgitation and in valvular and subvalvular stenosis could be detected. Cine MR imaging is a promising new technique for the evaluation of myocardial and valvular function.