Aging Curve of Neuromotor Function by Pronation and Supination of Forearms using Three-dimensional Wireless Acceleration and Angular Velocity Sensors
Aging Curve of Neuromotor Function by Pronation and Supination of Forearms using Three-dimensional Wireless Acceleration and Angular Velocity Sensors
复制标题
使用三维无线加速度和角速度传感器的前臂旋前和旋后神经运动功能的老化曲线
DOI：
10.1109/embc.2012.6346688
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Keiji Iramina
中科院分区：
文献类型：
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作者：
Miki Kaneko;Hirohi Okui;Go Hirakawa;Hiroshi Ishinishi,Yoshinori Katayama;Keiji Iramina
在本文中，我们报告了我们的研究与低频经颅磁刺激（rTMS）或短期rTMS刺激双侧缘上回（SMG）对大脑兴奋性的影响。分析不同刺激时间对事件相关电位（ERP）P300潜伏期的影响。使用8字形扁平线圈输送磁脉冲。rTMS的强度设置为受试者运动阈值的80%。在每轮rTMS中，在头皮上施加100个磁脉冲，频率为1.00、0.75和0.50 Hz。在磁刺激之前测量ERP作为对照。磁刺激的影响，然后确定其对P300潜伏期引起的一个奇怪的球任务的影响。在磁刺激前和磁刺激后0、5、10和15 min测量这些乳酸。1.00相反，0.50 Hz rTMS的左侧SMG导致延迟P300潜伏期约15分钟。我们还发现，0.75 Hz rTMS的左侧SMG和1.00，0.75和0.5 Hz rTMS的右侧SMG不影响P300潜伏期。这些结果表明，rTMS的影响的持续时间取决于刺激的频率。
In this paper, we report our studies of the effects of stimulating the bilateral supramarginal gyrus (SMG) with low-frequency transcranial magnetic stimulation (rTMS) or short-term rTMS on brain excitability in humans. We analyzed the effects of various durations of stimulation on P300 latencies of the event-related potential (ERP). Magnetic pulses were delivered using a figure-eight flat coil. The intensity of rTMS was set to 80% of the subject's motor threshold. In each round of rTMS, 100 magnetic pulses were applied over the scalp at frequencies of 1.00, 0.75, and 0.50 Hz. ERPs were measured prior to magnetic stimulation as a control. The effects of magnetic stimulation were then determined by measuring its effects on P300 latencies elicited by an odd-ball task. These latencies were measured before and 0, 5, 10, and 15 min after the magnetic stimulation. 1.00 Hz low-frequency rTMS of the left SMG decreased P300 latencies for approximately 10 min. In contrast, 0.50 Hz rTMS of the left SMG resulted in delayed P300 latencies for approximately 15 min. We furthermore found that 0.75 Hz rTMS of the left SMG and 1.00, 0.75 and 0.5 Hz rTMS of the right SMG did not affect P300 latencies. These results suggest that the duration of the effects of rTMS depend on the frequency of stimulation.