Optimization of acquisition parameters and accuracy of target motion trajectory for four-dimensional cone-beam computed tomography with a dynamic thorax phantom
Optimization of acquisition parameters and accuracy of target motion trajectory for four-dimensional cone-beam computed tomography with a dynamic thorax phantom
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动态胸部体模四维锥形束计算机断层扫描采集参数和目标运动轨迹精度优化
DOI：
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发表时间：
2014
影响因子：
1.6
通讯作者：
Yudai Kai
中科院分区：
文献类型：
--
作者：
Y. Shimohigashi;F. Araki;M. Maruyama;Y. Nakaguchi;K. Nakato;Nozomu Nagasue;Yudai Kai
本研究的目的是评估四维计算机断层扫描（4D-CBCT）的性能并优化采集参数。我们使用动态胸部模型评估了4D-CBCT的采集参数与目标运动轨迹准确性之间的关系。使用2 cm和3 cm的靶尺寸、4 s和8 s的呼吸周期以及1 cm和2 cm的振幅三维创建靶运动。4D-CBCT数据在两种探测器配置下采集：“小模式”和“中等模式”。将扫描时间范围为1至4分钟的投影数据分为2、5、10和15个相位箱。目标运动轨迹的测量精度进行了评估的均方根误差（RMSE）从设置值的装置。对于4 s的呼吸周期，所有采集时间和目标尺寸的测量轨迹均在设置值的2 mm范围内。同样，8 s呼吸周期的误差<4 mm。当我们使用10个或更多个相位箱时，测量的轨迹误差在设置值的2 mm内。两种探测器配置的轨迹误差显示出类似的趋势。对于4 s的呼吸周期，对于2 cm和3 cm的目标尺寸，实现RMSE为1 mm的采集时间分别为2 min和1 min。在这项研究中获得的结果，使目标大小，呼吸周期，和所需的测量精度的采集参数的优化。
Our purpose in this study was to evaluate the performance of four-dimensional computed tomography (4D-CBCT) and to optimize the acquisition parameters. We evaluated the relationship between the acquisition parameters of 4D-CBCT and the accuracy of the target motion trajectory using a dynamic thorax phantom. The target motion was created three dimensionally using target sizes of 2 and 3 cm, respiratory cycles of 4 and 8 s, and amplitudes of 1 and 2 cm. The 4D-CBCT data were acquired under two detector configurations: “small mode” and “medium mode”. The projection data acquired with scan times ranging from 1 to 4 min were sorted into 2, 5, 10, and 15 phase bins. The accuracy of the measured target motion trajectories was evaluated by means of the root mean square error (RMSE) from the setup values. For the respiratory cycle of 4 s, the measured trajectories were within 2 mm of the setup values for all acquisition times and target sizes. Similarly, the errors for the respiratory cycle of 8 s were <4 mm. When we used 10 or more phase bins, the measured trajectory errors were within 2 mm of the setup values. The trajectory errors for the two detector configurations showed similar trends. The acquisition times for achieving an RMSE of 1 mm for target sizes of 2 and 3 cm were 2 and 1 min, respectively, for respiratory cycles of 4 s. The results obtained in this study enable optimization of the acquisition parameters for target size, respiratory cycle, and desired measurement accuracy.
DOI：
10.1016/s0360-3016(02)02884-5
发表时间：
2002-08-01
影响因子：
7
作者：
Jaffray, DA;Siewerdsen, JH;Martinez, AA
通讯作者：
Martinez, AA
影响因子：
3.8
作者：
Vergalasova, Irina;Maurer, Jacqueline;Yin, Fang-Fang
通讯作者：
Yin, Fang-Fang
影响因子：
3.8
作者：
Shieh, Chun-Chien;Kipritidis, John;Keall, Paul J.
通讯作者：
Keall, Paul J.