Cerebrospinal angiostrongyliasis in five captive tamarins (Sanguinus spp)
Cerebrospinal angiostrongyliasis in five captive tamarins (Sanguinus spp)
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DOI：
10.1111/j.1751-0813.1998.tb10121.x
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发表时间：
1998-03-01
影响因子：
1.1
通讯作者：
Mudie, A
中科院分区：
文献类型：
--
作者：
Carlisle, MS;Prociv, P;Mudie, A
动物园里的四只棉顶狨猴（Sanguinus oedipus oedipus）和一只帝狨猴（S imperator subgrisescens）变得抑郁、厌食、截瘫，最终瘫痪。动物在出现临床症状后 5 天至 18 个月内死亡。组织学检查显示非化脓性和嗜酸性脑膜脑炎，在所有动物的蛛网膜下腔和一只动物的脊髓内发现后圆线虫幼虫。从一只动物的大脑中回收了具有与广州管圆线虫特征一致的完整幼虫。这种寄生虫是世界许多地区嗜酸粒细胞性脑膜脑炎的典型病因，根据临床情况可以强烈怀疑其诊断。在昆士兰州东南部等流行地区，保护圈养动物免受广州曲霉感染，在提供刺激的自然环境和消除潜在传染性的最终宿主、中间宿主和副感染宿主之间很难取得平衡。这是澳大利亚首次报道狨猴和非人灵长类动物脑脊髓血管圆线虫病。
Four cotton-top tamarins (Sanguinus oedipus oedipus) and one emperor tamarin (S imperator subgrisescens) housed in a zoo became depressed, anorexic, paraparetic and eventually paralysed. The animals died within 5 days to 18 months of the appearance of clinical signs. Histological examination showed nonsuppurative and eosinophilic meningoencephalitis, and metastrongyle nematode larvae were found within subarachnoid spaces of all animals and within the spinal cord of one. Intact larvae with features consistent with Angiostrongylus cantonensis were recovered from the brain of one animal. This parasite is the classical cause of eosinophilic meningoencephalitis in many parts of the world and the diagnosis can be strongly suspected on clinical grounds. In endemic areas like south-east Queensland, protection of captive animals against infection with A cantonensis is a difficult balance between providing a stimulating, natural setting and eliminating potentially infectious definitive, intermediate and paratenic hosts. This is the first report of cerebrospinal angiostrongyliasis in tamarins and nonhuman primates in Australia.