Increased co-morbidity of depression and post-traumatic stress disorder symptoms and common risk factors in intensive care unit survivors: A two-year follow-up study

Increased co-morbidity of depression and post-traumatic stress disorder symptoms and common risk factors in intensive care unit survivors: A two-year follow-up study
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DOI:
10.3109/13651501.2013.855793
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发表时间:
2014-01-01
影响因子:
3
通讯作者:
Kokras, Nikolaos
Kokras, Nikolaos
中科院分区:
医学4区
文献类型:
--
作者:
Paparrigopoulos, Thomas;Melissaki, Antigone;Kokras, Nikolaos

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目标。目的探讨重症监护病房(ICU)住院对患者的长期心理影响,并建立成功区分高危患者的危险因素。方法:研究方法。来自48名ICU幸存者的医疗结果研究简表调查(SF-36)、抑郁症流行病学研究中心(CES-D)和戴维森创伤量表(DTS)问卷也接受了采访,并就几个公认的危险因素进行了自我报告。结果。抑郁症和创伤后应激障碍(PTSD)的发病率很高。CES-D和DTS得分与SF-36心理健康子量表得分呈负相关;尽管不能归因于这一发现,但这表明即使在ICU后18至24个月,抑郁和创伤后应激障碍症状对患者的生活质量也有潜在的负面影响。与长期影响生活质量、抑郁症和创伤后应激障碍相关的最重要的风险因素是任何精神障碍的终生病史。结论。在ICU入院期间,应努力识别那些有精神病史的患者并在心理上给予支持,因为他们患上ICU入院的长期心理后遗症的风险相当高。
Objective. To investigate the long-term psychological impact of intensive care unit (ICU) hospitalization, as well as to establish risk factors which successfully discriminate patients at higher risk. Methods. The Medical Outcomes Study Short Form Survey (SF-36), the Center for Epidemiologic Studies for Depression (CES-D), and the Davidson Trauma Scale (DTS) questionnaires were obtained from 48 ICU survivors who were also interviewed and self-reported on several acknowledged risk factors. Results. A high co-morbidity between depression and post-traumatic stress disorder (PTSD) cases was observed. Both CES-D and DTS scores correlated negatively with the SF-36 mental health subscale scores; although a causative relation cannot be attributed to this finding, it indicates a potential negative impact of depression and PTSD symptoms on the patients' quality of life even at 18- to 24-month post-ICU. The most important risk factor associated with a long-term impact on quality of life, depression and PTSD was lifetime history of any psychiatric disorder. Conclusions. During ICU admissions efforts should be made towards identifying and psychologically supporting those patients with a previous history of a psychiatric disease, as they are at considerably higher risk of suffering from the long-term psychological sequelae of ICU admission.