The era of nitric oxide in plant biology: Twenty years tying up loose ends
The era of nitric oxide in plant biology: Twenty years tying up loose ends
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DOI：
10.1016/j.niox.2019.01.013
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发表时间：
2019-04-01
影响因子：
3.9
通讯作者：
Lamattina, Lorenzo
中科院分区：
文献类型：
--
作者：
Del Castello, Fiorella;Nejamkin, Andres;Lamattina, Lorenzo
一氧化氮（NO）是单细胞和多细胞生物维持细胞稳态的重要信号分子。从概念上讲，一氧化氮对维持基础代谢过程的干预程度与对内部和外部条件变化的细胞反应的干预程度一样多，也与引导回归基础条件的干预程度一样多。一氧化氮这些不寻常的能力背后是这种分子的化学性质，它是一种不稳定的、活性的、自由基和半衰期短的气体。它是一种亲脂分子，可以跨越生物膜所能施加的所有障碍。由NO调控的生理过程的阐明对植物产生的非凡影响，可与1986年发现NO存在于动物组织以及随后证明其调节血压的生物活性的深入研究的结果相媲美。在这篇综述中，我们总结和讨论了马德普拉塔大学在过去20年中出现的主要发现，这些发现有助于了解植物中NO的部分生物学。此外，将这些发现与其他研究小组的进展联系起来，强调植物中NO的历史才刚刚开始。
Nitric oxide (NO) is an essential signal molecule to maintain cellular homeostasis in uni and pluricellular organisms. Conceptually, NO intervenes as much in sustaining basal metabolic processes, as in firing cellular responses to changes in internal and external conditions, and also in guiding the return to basal conditions. Behind these unusual capabilities of NO is the chemistry of this molecule, an unstable, reactive, free radical and short half-life gas. It is a lipophilic molecule that crosses all the barriers that biological membranes can impose.The extraordinary impact that the elucidation of physiological processes regulated by NO has had on plants, is comparable to the consequences of the discovery in 1986 that NO is present in animal tissues, and the following deep studies that demonstrated its biological activity regulating blood pressure.In this review, we have summarized and discuss the main discoveries that have emerged at Mar del Plata University over the past 20 years, and that have contributed to understand part of the biology of NO in plants. Besides, these findings are put in context with the progress made by other research groups, and in perspective, emphasizing that the history of NO in plants has just begun.