Cerebral blood flow velocity before and after cerebrospinal fluid drainage in infants with posthemorrhagic hydrocephalus
Cerebral blood flow velocity before and after cerebrospinal fluid drainage in infants with posthemorrhagic hydrocephalus
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DOI：
10.7863/jum.2004.23.10.1315
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发表时间：
2004-10-01
影响因子：
2.3
通讯作者：
Akamatsu, H
中科院分区：
文献类型：
--
作者：
Nishimaki, S;Iwasaki, Y;Akamatsu, H
Objective.目前，脑出血后脑积水婴儿的脑脊液（CSF）引流时间和量由主观临床表现决定。本研究的目的是确定阻力指数的测量是否对这些婴儿的CSF引流管理有用。方法.应用脉冲多普勒超声检测了7例脑出血后脑积水婴儿在腰穿或皮下脑室导管储液囊穿刺前后大脑前动脉阻力指数（RI-ACA）。结果以5 - 10 mL/kg的速率移除CSF后，增加的RI-ACA值（平均值+/- SD，0.86 +/- 0.04;范围，0.80-0.89）显著降低（0.76 +/- 0.05; 0.64-0.83）（P < .0001）。结论.我们认为，RI-ACA的测量可能有助于评估CSF引流的疗效，并确定脑积水婴儿应清除多少CSF。
Objective. Currently, the timing and volume of cerebrospinal fluid (CSF) drainage are determined by subjective clinical findings in infants with posthemorrhagic hydrocephalus. The aim of this study was to determine whether measurement of the resistive index is useful for management of CSF drainage in these infants. Methods. We measured the resistive index in the anterior cerebral artery (RI-ACA) by using pulsed Doppler sonography before and after lumbar or subcutaneous ventricular catheter reservoir punctures in 7 infants with posthemorrhagic hydrocephalus. Results. The increased RI-ACA values (mean +/- SD, 0.86 +/- 0.04; range, 0.80-0.89) decreased significantly (0.76 +/- 0.05; 0.64-0.83) after removal of CSF at a rate of 5 to 10 mL/kg (P < .0001). Conclusions. We suggest that measurement of the RI-ACA may be useful for evaluating the efficacy of CSF drainage and to determine how much CSF should be removed in hydrocephalic infants.