AtFH14 crosslinks actin filaments and microtubules in different manners
AtFH14 crosslinks actin filaments and microtubules in different manners
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AtFH14 以不同方式交联肌动蛋白丝和微管
DOI：
10.1111/boc.202000147
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发表时间：
2021-02-01
影响因子：
2.7
通讯作者：
Ren, Haiyun
中科院分区：
文献类型：
--
作者：
Du, Pingzhou;Wang, Jiaojiao;Ren, Haiyun
在包括细胞分裂在内的许多细胞过程中，肌动蛋白丝和微管的协同动力学起着至关重要的作用。然而，这些协同动力学的调节机制尚不完全清楚。formmins等蛋白参与肌动蛋白丝与微管的相互作用，拟南芥formin 14 （AtFH14）可能在细胞分裂过程中作为肌动蛋白丝与微管之间的交联剂，但这种交联的分子机制尚不清楚。
In many cellular processes including cell division, the synergistic dynamics of actin filaments and microtubules play vital roles. However, the regulatory mechanisms of these synergistic dynamics are not fully understood. Proteins such as formins are involved in actin filament–microtubule interactions and Arabidopsis thaliana formin 14 (AtFH14) may function as a crosslinker between actin filaments and microtubules in cell division, but the molecular mechanism underlying such crosslinking remains unclear.