Six new recombinant inbred populations for the study of quantitative traits in Arabidopsis thaliana
Six new recombinant inbred populations for the study of quantitative traits in Arabidopsis thaliana
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DOI：
10.1007/s00122-007-0696-9
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发表时间：
2008-03-01
影响因子：
5.4
通讯作者：
Bancroft, Ian
中科院分区：
文献类型：
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作者：
O'Neill, Carmel M.;Morgan, Colin;Bancroft, Ian
定量方法现在被广泛用于研究复杂性状的遗传结构。然而，大多数研究都是在单一定位群体中进行的，这些群体仅对基因库中可用的一小部分天然等位基因变异进行采样，并且只能识别控制性状的基因座的一个子集。为了能够在了解广泛复杂性状的全球遗传结构方面取得进展，我们开发了六个新的拟南芥重组近交群体并进行了表征。为了评估这些群体的效用，从多个群体的整合分析，我们确定了数量性状基因座（QTL）控制开花时间春化植物生长在16小时天。我们使用标记的物理位置来将我们的群体的连锁图与六个现有群体的连锁图进行比对。我们确定了7个QTL的基因组位置与以前的研究中确定的一致，此外，另外8个QTL被确定。
Quantitative approaches are now widely used to study the genetic architecture of complex traits. However, most studies have been conducted in single mapping populations, which sample only a fraction of the natural allelic variation available within a gene pool and can identify only a subset of the loci controlling the traits. To enable the progress towards an understanding of the global genetic architecture of a broad range of complex traits, we have developed and characterised six new Arabidopsis thaliana recombinant inbred populations. To evaluate the utility of these populations for integrating analyses from multiple populations, we identified quantitative trait loci (QTL) controlling flowering time in vernalized plants growing in 16 h days. We used the physical positions of markers to align the linkage maps of our populations with those of six existing populations. We identified seven QTL in genomic locations coinciding with those identified in previous studies and in addition a further eight QTL were identified.