Default mode network connectivity:: effects of age sex, and analytic approach
Default mode network connectivity:: effects of age sex, and analytic approach
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DOI：
10.1097/wnr.0b013e328300ebbf
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发表时间：
2008-05-28
期刊：
影响因子：
1.7
通讯作者：
Williamson, Peter
中科院分区：
文献类型：
--
作者：
Bluhm, Robyn L.;Osuch, Elizabeth A.;Williamson, Peter
“默认模式网络”是一组大脑区域，在休息时表现出相关的低频活动。它包括后扣带/楔前叶、内侧前额叶皮质和双侧下顶叶皮质。早期的研究已经使用基于兴趣区域的相关性分析或数据驱动技术来表征这个网络;然而，对于哪种方法更上级存在一些分歧。我们对一个大型（N=40）数据集进行了两种类型的分析，并调查了网络中的年龄和性别差异。两个区域的利益为基础的分析和独立成分分析确定的默认模式网络。年龄和性别的差异很小，有较少的协议之间的分析技术对年龄和性别的影响比默认模式的网络结构。
The 'default mode network' is a set of brain regions showing correlated, low-frequency activity during rest. It includes the posterior cingulate/precuneus, medial prefrontal cortex, and bilateral inferior parietal cortex. Earlier studies have characterized this network using either region of interest-based correlation analyses or data-driven techniques; however, there is some disagreement over which method is superior. We conducted both types of analysis on a large (N=40) data set and also investigated age and sex differences in the network. Both region of interest-based analyses and independent component analysis identified the default mode network. Age and sex differences were small and there was less agreement between analytic techniques regarding age and sex effects than regarding default mode network structure.