Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.
Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells.
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HEK 293 细胞中表达的大鼠神经元烟碱受体亚型的激动剂结合位点的药理学。
DOI：
10.1016/j.bmcl.2003.09.105
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发表时间：
2004
影响因子：
2.7
通讯作者：
Kellar,KennethJ
中科院分区：
文献类型：
--
作者：
Xiao,Yingxian;Baydyuk,Maryna;Wang,HaizhuPearl;Davis,HeatherE;Kellar,KennethJ
The binding affinities of agonists at heteromeric nicotinic receptors composed of rat α2, α3 and α4 subunits in combination with β2 or β4 subunits were examined in stably transfected HEK 293 cells. In most cases, the affinities of agonists were higher at receptors composed of an α subunit in combination with the β2 subunit than the β4 subunit, and in some cases this difference was quite large (>250 times), suggesting the possibility of developing subtype-selective ligands and therapeutically useful drugs.
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影响因子：
3.6
作者：
Avila,AmyM;Dávila-García,MarthaI;Ascarrunz,VeronicaS;Xiao,YingxIan;Kellar,KennethJ
通讯作者：
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DOI：
--
发表时间：
1997
期刊：
The Journal of pharmacology and experimental therapeutics
影响因子：
--
作者：
Dávila-García,MI;Musachio,JL;Perry,DC;Xiao,Y;Horti,A;London,ED;Dannals,RF;Kellar,KJ
通讯作者：
Kellar,KJ
影响因子：
3.6
作者：
Christopher M. Flores;Scott W. Rogers;L. Pabreza;B. Wolfe;K. Kellar
通讯作者：
Christopher M. Flores;Scott W. Rogers;L. Pabreza;B. Wolfe;K. Kellar
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DOI：
--
发表时间：
1992
期刊：
影响因子：
--
作者：
A. Figl;B. Cohen;M. Quick;N. Davidson;H. Lester
通讯作者：
H. Lester