Simple conjugated polymer nanoparticles as biological labels
Simple conjugated polymer nanoparticles as biological labels
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DOI：
10.1098/rspa.2009.0181
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发表时间：
2009-09-08
影响因子：
3.5
通讯作者：
Thanou, Maya
中科院分区：
文献类型：
--
作者：
Green, Mark;Howes, Philip;Thanou, Maya
纳米粒子在生物学中的应用，特别是在细胞成像中，是非常有前途的，并提供了许多优于现有有机染料系统的优点。然而，在实现此类材料在主流临床应用中的使用之前，需要解决一些限制。其中一个主要问题是使用含金属的颗粒，这些颗粒可能有毒或干扰其他诊断过程。在这里，我们提出了使用简单的共轭聚合物纳米粒子作为替代光稳定的细胞光学成像剂。
The use of nanoparticles in biology, especially in cellular imaging, is extremely promising and offers numerous advantages over existing organic dye systems. There are, however, constraints that need to be addressed before the use of such materials in mainstream clinical applications can be realized. One of the main concerns is the use of metal-containing particles that are potentially toxic or interfere with other diagnostic processes. Here, we present the use of simple conjugated polymer nanoparticles as alternative photostable cellular optical imaging agents.