Hepatic lesions: Discrimination of nonsolid, benign lesions from solid, malignant lesions with heavily T2-weighted fast spin-echo MR imaging
Hepatic lesions: Discrimination of nonsolid, benign lesions from solid, malignant lesions with heavily T2-weighted fast spin-echo MR imaging
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DOI：
10.1148/radiology.204.3.9280251
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发表时间：
1997-09-01
期刊：
影响因子：
19.7
通讯作者：
Sadek, AG
中科院分区：
文献类型：
--
作者：
Ito, K;Mitchell, DG;Sadek, AG
目的：确定联合使用重度和中度 T2 加权快速自旋回波磁共振 (MR) 图像是否可以改善非实体良性肝脏病变与实体恶性肿瘤的鉴别。 材料和方法：三位放射科医生审查了 133 例中度（n = 133）和重度（n = 133）T2 加权和多相动态对比材料增强（n = 93）MR 图像。已证实患有局灶性肝脏病变的患者（95 例良性，38 例恶性）。放射科医生使用五点量表来评估他们对确定恶性肿瘤的信心。结果：与单独使用中等 T2 加权图像（面积， 0.88-0.90；P<0.05)。结合使用中度和重度 T2 加权图像，对 69 名 (82%) 患者做出了可信的诊断，准确率达到 100%。对于较大的病变（直径 3 厘米或更大；n = 49），仅使用中等 T2 加权图像就可以准确区分。额外使用多相图像并没有提高图像判读的敏感性、特异性或准确性。结论：中度和重度 T2 加权快速自旋回波 MR 图像的联合使用提高了小型良性肝脏病变与小型恶性病变的区分。
PURPOSE: To determine whether the combined use of heavily and moderately T2-weighted fast spin-echo magnetic resonance (MR) images improves differentiation of nonsolid, benign hepatic lesions from solid malignancies.MATERIALS AND METHODS: Three radiologists reviewed moderately (n = 133) and heavily (n = 133) T2-weighted and multiphasic dynamic contrast material-enhanced (n = 93) MR images in 133 patients with proved focal hepatic lesions (95 benign, 38 malignant). The radiologists used a five-point scale to rate their confidence in determination of malignancy.RESULTS: All three reviewers were statistically significantly better able to differentiate small (diameter less than 3 cm; n = 84) benignancies from small malignancies with the combination of moderately and heavily T2-weighted images (area under the receiver operating characteristic curve, 0.99 for each reader) than with moderately T2-weighted images alone (area, 0.88-0.90; P < .05). Confident diagnoses were rendered in 69 (82%) patients, with 100% accuracy for the combined use of moderately and heavily T2-weighted images. For larger lesions (diameter 3 cm or larger; n = 49), accurate differentiation was possible with moderately T2-weighted images alone. Additional use of multiphasic images did not improve the sensitivity, specificity, or accuracy of image interpretation.CONCLUSION: The combined use of moderately and heavily T2-weighted fast spin-echo MR images improves differentiation of small benign hepatic lesions from small malignant lesions.