Physical activity and cardiovascular disease in African Americans in Atherosclerosis Risk in Communities.
Physical activity and cardiovascular disease in African Americans in Atherosclerosis Risk in Communities.
复制标题
DOI：
10.1249/mss.0b013e31827d87ec
复制
发表时间：
2013-05
影响因子：
4.1
通讯作者：
Folsom AR
中科院分区：
文献类型：
--
作者：
Bell EJ;Lutsey PL;Windham BG;Folsom AR
虽然有大量证据表明，体育活动可以降低一个人患心血管疾病（CVD）的风险，但这些研究中很少包括非洲裔美国人。包括非洲裔美国人的研究提供了关于这种关联的非决定性证据，并且没有单独研究心力衰竭。我们使用来自社区动脉粥样硬化风险研究队列的数据，在非裔美国人中检查身体活动与CVD及其主要组成部分-中风，心力衰竭和冠心病发病率的相关性。年龄在45至64岁之间的参与者（3，707名非洲裔美国人和10，018名白人）在1987年通过问卷调查进行了体力活动评估，并在2008年对CVD事件（n= 1，039）进行了随访。校正潜在混杂因素后，体力活动与两个种族的CVD、心力衰竭和冠心病发病率呈负相关（趋势p值<0.0001），与非裔美国人的中风呈负相关。风险比每个较高体力活动类别的CVD（95%置信区间）按种族相似：1.0，0.65（0.56，0.75）和0.59非裔美国人为1.0、0.74（0.66，0.83）和0.67（0.59，0.75）（相互作用的p值= 0.38）。我们的研究结果强化了这样的建议，即定期的体育活动对降低非裔美国人和高加索人的心血管疾病风险很重要，并支持一些体育活动总比没有好的观点。
Although there is substantial evidence that physical activity reduces a person's risk of cardiovascular disease (CVD), few of these studies have included African Americans. The studies that have included African Americans offer inconclusive evidence on the association and none studied heart failure separately. We used data from the Atherosclerosis Risk in Communities study cohort to examine, in African Americans, the association of physical activity with the incidence of CVD and its major components – stroke, heart failure, and coronary heart disease. Participants aged 45 to 64 years (3,707 African Americans and, for comparison, 10,018 Caucasians) had physical activity assessed via questionnaire in 1987 and were followed for incident CVD (n=1,039) through 2008. After adjustment for potential confounders, physical activity was inversely related to CVD, heart failure, and coronary heart disease incidence in both races (p-values for trend <.0001), and with stroke in African Americans. Hazard ratios (95% confidence intervals) for CVD for each higher physical activity category were similar by race: 1.0, 0.65 (0.56, 0.75), and 0.59 (0.49, 0.71) for African Americans and 1.0, 0.74 (0.66, 0.83), and 0.67 (0.59, 0.75) for Caucasians (p-value for interaction = 0.38). Our findings reinforce recommendations that regular physical activity is important for CVD risk reduction in African Americans as well as Caucasians and support the idea that some physical activity is better than none.