Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH
Loop nucleotides impact the stability of intrastrand i-motif structures at neutral pH
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DOI：
10.1039/c5cp02794b
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发表时间：
2015-01-01
影响因子：
3.3
通讯作者：
Sugimoto, Naoki
中科院分区：
文献类型：
--
作者：
Fujii, Taiga;Sugimoto, Naoki
i基序结构在中性pH下的稳定性是令人感兴趣的，因为这些结构可能影响基因表达。环序列和长度的系统研究表明，某些环核碱基稳定的i-基序四链体。
The stability of i-motif structures at neutral pH is of interest due to the potential of these structures to impact gene expression. A systematic investigation of loop sequence and length revealed that certain loop nucleobases stabilize i-motif quadruplexes.