FUNCTIONAL-ANATOMY OF SYMPATHETIC PREMOTOR CELL GROUPS IN THE MEDULLA
FUNCTIONAL-ANATOMY OF SYMPATHETIC PREMOTOR CELL GROUPS IN THE MEDULLA
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DOI：
10.3109/10641969509087066
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发表时间：
1995-01-01
影响因子：
12.3
通讯作者：
SHAFTON, AD
中科院分区：
文献类型：
--
作者：
MCALLEN, RM;MAY, CN;SHAFTON, AD
节前和节后交感神经元根据它们提供的目标被组织成离散的功能通道。它们显示的活动模式在不同通道之间有所不同，这意味着驱动它们的中枢神经系统路径并不相同。前运动神经元可能发挥着关键作用。本文重点介绍最近的证据告诉我们有关控制特定交感神经流出的运动前神经元的组织。已在延髓头端腹外侧 (RVLM) 的运动前神经元中鉴定出驱动肌肉血管收缩细胞 (MVC)、皮肤血管收缩细胞 (CVC)、内脏血管收缩细胞 (VVC) 和肾交感神经 (RSN) 流出的细胞。其他血管舒缩、心脏或肾上腺驱动也出现在该细胞组中。驱动催汗反应的神经元位于延髓头侧腹内侧。简要讨论了其他前运动细胞群的特定功能的证据。
Pre- and postganglionic sympathetic neurons are organized into discrete functional channels, according to the target they supply. The activity patterns which they show differ between channels, implying that the CNS pathways driving them are not the same. Premotor neurons probably play a key role. This article focuses on what recent evidence tells us about the organization of premotor neurons which control specific sympathetic outflows. Cells that drive muscle vasoconstrictor (MVC), cutaneous vasoconstrictor (CVC), visceral vasoconstrictor (VVC) and renal sympathetic (RSN) outflows have been identified among the premotor neurons of the rostral ventrolateral medulla (RVLM). Other vasomotor, cardiac or adrenal drives are also represented in that cell group. Neurons driving sudomotor responses have been localized in the rostral ventromedial medulla. Evidence on the specific functions of other premotor cell groups is briefly discussed.