Number, characteristics, and classification of patients with dermatomyositis seen by dermatology and rheumatology departments at a large tertiary medical

Number, characteristics, and classification of patients with dermatomyositis seen by dermatology and rheumatology departments at a large tertiary medical
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DOI:
10.1016/j.jaad.2007.08.024
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发表时间:
2007-12-01
影响因子:
13.8
通讯作者:
Werth, Victoria P.
Werth, Victoria P.
中科院分区:
医学1区
文献类型:
--
作者:
Klein, Rhonda Q.;Teal, Valerie;Werth, Victoria P.

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背景:目前皮肌炎(DM)的诊断标准排除了无肌肉受累的患者。因此,缺乏与疾病的完整谱相关的研究。本研究的目的是评估皮肤科与风湿科糖尿病临床表现的差异。我们假设,最低限度(hypomyopathic)或无(amyopathic)肌肉疾病的患者更有可能被视为在皮肤科,而那些更严重的(经典)肌肉疾病将被视为在rheology.Methods:我们进行了回顾性图表审查的DM患者看到我们的皮肤科和rheology. Methods部门分类光谱,介绍和并发症。2003年7月1日至2006年6月30日期间就诊的患者通过Cui-rent手术术语计费代码710.3进行识别。排除混合性结缔组织病或错误编码的DM患者。总共确定了131例(65%)皮肤科患者,58例(29%)风湿科患者和13例(6%)两个科室的患者。共有83名(69%)皮肤科患者、27名(23%)风湿科患者和10名(8%)两个科室的患者符合纳入研究的标准。根据经典DM(CDM)分类,在风湿病学中观察到的患者数量(24/27 [89%]),低肌病性DM(2/27 [7%]),无肌病性DM(ADM)0/27 [4%])与皮肤科显著不同,其中CDM占83例中的27例(33%),低肌病性DM占83例中的23例(28%),ADM和ADM分别占33/83(40%)(P
Background: The current diagnostic criteria for dermatomyositis (DM) exclude patients without muscle involvement. As a result there is a paucity of research related to the complete spectrum of the disease.Objective:. The goal of this study was to evaluate differences in the clinical manifestations of DM seen by dermatology relative to rheumatology. We hypothesized that patients with minimal (hypomyopathic) or no (amyopathic) muscle disease would more likely be seen in dermatology, whereas those with more severe (classic) muscle disease would be seen in rheumatology.Methods: We performed a retrospective chart review of patients with DM seen by our dermatology and rheumatology departments to classify spectrum, presentation, and complications. Patients seen between July 1, 2003, and June 30, 2006, were identified by Cui-rent Procedural Terminology billing code 710.3. Patients with mixed connective tissue diseases or miscoded DM were excluded.Results. In all, 131 (65%) patients seen in dermatology, 58 (29%) in rheumatology, and 13 (6%) in both departments were identified. In all, 83 (69%) patients seen in dermatology, 27 (23%) in rheumatology, and 10 (8%) in both departments met criteria for inclusion in the study. The number of patients seen in rheumatology given the classification of classic DM (CDM) (24 of 27 [89%]), hypomyopathic DM (2 of 27 [7%]), and amyopathic DM (ADM) 0 of 27 [4%]) differed significantly from dermatology, where CDM comprised 27 of 83 (33%), hypomyopathic DM comprised 23 of 83 (28%), and ADM comprised 33 of 83 (40%) of the population, respectively (P