Attitudes toward clinical trials among patients and the public.
Attitudes toward clinical trials among patients and the public.
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患者和公众对临床试验的态度。
DOI：
10.1001/jama.1982.03330080050028
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
S. Hurwitz
中科院分区：
文献类型：
--
作者：
B. Cassileth;E. Lusk;D. Miller;S. Hurwitz
对临床研究的态度，最近和破坏性的媒体关注的焦点，通过匿名完成的问卷调查104例癌症患者，84名心脏病患者，和107名普通公众进行了评估。反应不同，既不亚组，也不人口统计学变量。因此，报告了295例受试者总人群的数据。大多数受访者（71%）认为，患者应作为研究对象。为了支持这一观点，大多数人提到了对他人的潜在利益和增加科学知识的机会，但当他们被问及自己的潜在参与时，出现了不同的偏见。这项研究表明，不同的受访者认为临床试验是重要的，道德的，并作为一种手段，实现上级临床护理。最重要的是对医学知识的贡献和帮助未来的病人。在病人对他们自己的治疗和对“假设的他人”的治疗的看法上，有明显的对比。"
Attitudes toward clinical research, the focus of recent and damaging media attention, were assessed through questionnaires completed anonymously by 104 patients with cancer, 84 cardiology patients, and 107 members of the general public. Responses differed neither by subgroup nor by demographic variables. Data are therefore reported on the total population of 295 subjects. Most respondents (71%) believed that patients should serve as research subjects. In support of this belief, the majority cited potential benefit ot others and the opportunity to increase scientific knowledge, but a different bias emerged when they were asked about their own potential participation. This study shows that diverse respondents view clinical trials as important, ethical, and as a means of attaining superior clinical care. Major importance is attributed to making contributions to medical knowledge and to helping future patients. Contrasts are noted in patients' views of their own treatments v treatments of "'hypothetical others."