The effects of induction electric field on sensitivity of firing rate in a single-compartment neuron model
The effects of induction electric field on sensitivity of firing rate in a single-compartment neuron model
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DOI：
10.1016/j.neucom.2012.04.032
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发表时间：
2013
期刊：
影响因子：
6
通讯作者：
Xiuxiu Wang;Jiang Wang;Bin Deng;Xile Wei;Huiyan Li
中科院分区：
文献类型：
--
作者：
Xiuxiu Wang;Jiang Wang;Bin Deng;Xile Wei;Huiyan Li
神经编码是神经元对外界刺激做出反应的重要方式之一。本文在简化的Hodgkin-Huxley（HH）模型的基础上，建立了一个新的单室神经元模型。我们研究了神经元如何编码外部刺激以及神经元放电率对噪声的敏感性。在分岔点处分别加入直流噪声IEF（DCIEF）和交流噪声IEF（ACIEF）。通过数值模拟，我们发现IEF的频率和幅度对神经元放电率的敏感性有显著影响。这些结果可能对神经信息处理有重要意义。
Neural coding is one of the most important ways for neurons responding to external stimuli. In this paper, a new single-compartment neuron model in the effect of induction electric field (IEF) is established based on a simplified Hodgkin–Huxley (HH) model. We investigate how a neuron encodes the external stimulus and the sensitivity of neuronal firing rate to noises. Noisy direct current IEF (DCIEF) and alternating current IEF (ACIEF) are added into the model at the bifurcation point, respectively. Through numerical simulation, we show that frequency and amplitude of the IEF have significant influences on the sensitivity of neuronal firing rate. The presented results may have important implications for neural information processing.