Hippocampal volume measurements using magnetic resonance imaging in normal young adults.
Hippocampal volume measurements using magnetic resonance imaging in normal young adults.
复制标题
使用磁共振成像测量正常年轻人的海马体积。
DOI：
10.1111/jon19955295
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Smith,CD
中科院分区：
文献类型：
--
作者：
Honeycutt,NA;Smith,CD
脑磁共振图像（MRI）的体积分析测量与神经和神经精神障碍相关的结构变化。有几项研究专门研究了海马体，报告了这类疾病的萎缩程度。然而，正常海马体积的范围必须是已知的评估萎缩。本文报告24例正常人的T1斜断层和三维磁共振成像，右侧和左侧海马的平均体积分别为2.90 cm 3和2.78 cm 3。在配对分析中，这种差异是显著的。文献表明，在基于MRI和基于组织学的研究中，这些体积处于海马体积范围（1.73-5.68 cml）的中间。Th 1的广泛变化可以通过不同的海马边界定义、图像处理、分割和显示的技术因素、样本异质性和操作者差异来解释。
Volumetric analysis of brain magnetic resonance images (MRIs) measures structural changes associated with neurological and neuropsychiatnc disorders. Several studies investigated the hippocampus specifically, report1ng degrees of atrophy in such disorders. However, the range of normal hippocampal volumes must be known to assess atrophy. In tracings of T1 oblique slice and three‐dimensional MRis 1n 24 normal subjects reported here, the average volume of right and left hippocampus was 2.90 cm3 and 2.78 cm3, respectively. On paired analys1s, this difference was significant The literature Indicated these volumes are in the m1ddle of a wide range of hippocampal volumes (1.73–5.68 cml) 1n both MRI‐based and histology‐based studies. Th1s wide variation can be expla1ned by differing hippocampal boundary definitions; technical factors of image processing, segmentation, and display; sample heterogeneity; and interoperator differences.