The application of a new method of limb blood flow measurement using a radioactive isotope and a gamma camera.
The application of a new method of limb blood flow measurement using a radioactive isotope and a gamma camera.
复制标题
使用放射性同位素和伽马相机测量肢体血流的新方法的应用。
DOI：
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发表时间：
1989
影响因子：
1.4
通讯作者：
R. C. Kester
中科院分区：
文献类型：
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作者：
D. Wilkinson;A. Parkin;P. Wowden;Robinson Pj;R. C. Kester
为了评估使用放射性同位素和伽马相机测量肢体血流的新方法，对 108 名周围血管疾病患者进行了血流测量。 36 名患者患有缺血性静息痛，其中两人此前曾接受过单侧截肢。其中 5 例出现双侧症状，其中 29 例肢体无症状，41 例肢体严重缺血。对 72 名间歇性跛行患者进行了一系列运动测试，其中 33 名结果不令人满意； 13 名患者在四次测试之间的最大步行距离变异大于 20%，其中 20 名患者的步行距离受到跛行以外的因素的限制。在这 33 名患者中，流向有症状腿部的肢体血流量为 3.95 (1.36-11.08) ml/100 ml 组织/分钟。这与 39 名患者的有症状腿部的肢体血流量没有显着差异，这些患者满意地完成了四次运动测试，即 3.75（1.08-8.25）ml/100ml 组织/分钟。在这 39 名患者中，平均无痛步行距离为 40 米，平均最大步行距离为 63 米。 36名静息痛患者41个有症状肢体的肢体血流量为1.90（0.90-4.49）ml/100ml组织/分钟，明显低于跛行患者的血流量。所有患者无症状四肢的血流量值存在很大差异，并且在许多情况下血流量明显低于正常值。这种肢体血流量测量方法准确且重复性好，可推荐用于评估周围血管疾病。
To evaluate a new method for limb blood flow measurement using a radioactive isotope and a gamma camera, blood flow measurements have ben made on 108 patients with peripheral vascular disease. Thirty-six patients had ischaemic rest pain, of whom two had previously undergone unilateral amputation. Five had bilateral symptoms, giving 29 asymptomatic limbs and 41 limbs with critical ischaemia. In 72 patients with intermittent claudication a series of exercise tests were attempted, in 33 these were unsatisfactory; 13 patients had a greater than 20% variability in the maximum walking distance between four tests and in 20 walking distance was limited by factors other than claudication. In these 33 patients the limb blood flow to the symptomatic leg was 3.95 (1.36-11.08) ml/100 ml of tissue/minute. This is not significantly different from the limb blood flow to the symptomatic leg of the 39 patients who satisfactorily completed four exercise tests, 3.75 (1.08-8.25) ml/100 ml of tissue/minute. In these 39 patients the mean pain-free walking distance was 40 metres and the mean maximum walking distance was 63 metres. The limb blood flow to the 41 symptomatic limbs of 36 patients with rest pain was 1.90 (0.90-4.49) ml/100 ml of tissue/minute, which is significantly less than that obtained in claudicants. There was a wide range of blood flow values found in the asymptomatic limbs of all the patients and in many cases the flow was markedly reduced from normal. This method of limb blood flow measurement is accurate and reproducible and may be recommended for assessment of peripheral vascular disease.