Platinum-Catalyzed Cycloisomerization Reaction of 1,6-Enyne Coupling with Rearrangement of Propargylic Esters
Platinum-Catalyzed Cycloisomerization Reaction of 1,6-Enyne Coupling with Rearrangement of Propargylic Esters
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铂催化 1,6-烯炔偶联环异构化反应及炔丙酯重排
DOI：
10.1021/jo802043z
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发表时间：
2009-01-02
影响因子：
3.6
通讯作者：
Liang, Yong-Min
中科院分区：
文献类型：
--
作者：
Lu, Li;Liu, Xue-Yuan;Liang, Yong-Min
发展了一种铂催化的炔丙酯重排反应与1，6-烯炔环异构化反应的偶联反应。最有可能的是，在铂催化下，炔丙酯经历1，3-酰氧基迁移，得到金属丙二烯中间体，然后进行Diels-Alder型反应。1，3-酰氧基迁移是转化过程中的关键步骤。
A platinum-catalyzed cycloisomerization of 1,6-enyne coupling with the rearrangement chemistry of propargylic ester has been developed. Most probably, under platinum catalysis, propargylic ester undergoes the 1,3-acyloxy migration to afford metal allene intermediate, which is followed by the Diels-Alder-type reaction. 1,3-Acyloxy migration is the key step during the transformation.