SimVascular: An Open Source Pipeline for Cardiovascular Simulation.

SimVascular: An Open Source Pipeline for Cardiovascular Simulation.
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DOI:
10.1007/s10439-016-1762-8
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发表时间:
2017-03
影响因子:
3.8
通讯作者:
Shadden SC
Shadden SC
中科院分区:
工程技术2区
文献类型:
--
作者:
Updegrove A;Wilson NM;Merkow J;Lan H;Marsden AL;Shadden SC

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针对特定患者的心血管仿真已成为心血管研究的一个范例,并正在成为基础、转化和临床研究的一个有力工具。在本文中,我们讨论了一个完全开源的SimVascular软件包,它提供了一个完整的管道从医学图像数据分割到患者特定的血流模拟和分析的最新发展。该软件包可作为心血管建模和仿真的研究工具,并为个性化医疗、手术规划和医疗设备设计方面的许多进步做出了贡献。最近对SimVascular软件进行了重构和扩展,以增强基于图像的患者特定建模工具的功能、可用性、效率和准确性。此外,SimVascular以前需要几个许可组件,这阻碍了新用户的采用和代码管理,我们最近的开发已经取代了这些商业组件,以创建一个完全开源的管道。这些发展促进了心血管建模研究的进步,增加了合作,方法标准化以及不断增长的开发人员社区。
Patient-specific cardiovascular simulation has become a paradigm in cardiovascular research and is emerging as a powerful tool in basic, translational and clinical research. In this paper we discuss the recent development of a fully open-source SimVascular software package, which provides a complete pipeline from medical image data segmentation to patient-specific blood flow simulation and analysis. This package serves as a research tool for cardiovascular modeling and simulation, and has contributed to numerous advances in personalized medicine, surgical planning and medical device design. The SimVascular software has recently been refactored and expanded to enhance functionality, usability, efficiency and accuracy of image-based patient-specific modeling tools. Moreover, SimVascular previously required several licensed components that hindered new user adoption and code management and our recent developments have replaced these commercial components to create a fully open source pipeline. These developments foster advances in cardiovascular modeling research, increased collaboration, standardization of methods, and a growing developer community.
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