Embryogenesis without CTCF in flies and vertebrates.
Embryogenesis without CTCF in flies and vertebrates.
复制标题
果蝇和脊椎动物无 CTCF 的胚胎发生。
DOI:
10.1038/s41594-021-00662-x
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发表时间:
2021
影响因子:
16.8
通讯作者:
Nora,ElphègeP
中科院分区:
文献类型:
--
作者:
Fudenberg,Geoffrey;Nora,ElphègeP
CTCF is a conserved DNA- and RNA-binding protein with roles in genome folding and transcriptional regulation. Two recent studies investigated how CTCF knockout perturbs genome biology and derails embryogenesis in zebrafish andDrosophila melanogaster, revealing contrasting effects across species.