Estimated 10-year stroke risk by region and race in the United States: geographic and racial differences in stroke risk.
Estimated 10-year stroke risk by region and race in the United States: geographic and racial differences in stroke risk.
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DOI：
10.1002/ana.21493
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发表时间：
2008-11
影响因子：
11.2
通讯作者：
Howard, Virginia J.
中科院分区：
文献类型：
--
作者：
Cushman, Mary;Cantrell, Ronald A.;McClure, Leslie A.;Howard, George;Prineas, Ronald J.;Moy, Claudia S.;Temple, Ella M.;Howard, Virginia J.
75岁以下的非洲裔美国人中风死亡的风险是美国白人的两倍多。无论种族如何，在美国东南部的“中风带”和“中风带”州，中风死亡率高出约50%。我们评估了10年中风风险估计的地理和种族差异。卒中的地理和种族差异的原因研究是一项基于人群的队列研究，招募年龄≥45岁的男性和女性，2003年2月至2007年9月在本报告中，对卒中带/扣居民和非洲裔美国人进行了过采样。在23，940名既往无卒中或短暂性脑缺血发作的参与者中研究了卒中风险评分的种族和地区差异。年龄、种族和性别调整后的平均10年预测卒中概率在不同地区略有不同;腰带区为10.7%，带扣区为10.4%，其他地区为10.1%（p <0.001）。糖尿病评分和抗高血压治疗使用的地理差异最大。非裔美国人的年龄和性别校正的平均10年预测卒中概率高于白人，分别为11.3%和9.7%（p <0.001）。高血压、收缩压、糖尿病、吸烟和左心室肥大的评分组分的种族差异最大。虽然非洲裔美国人的预测中风概率高于白人，但地区差异很小。结果表明，减少卒中危险因素种族差异的干预措施有望减少卒中死亡率的种族差异。中风死亡率的地理差异可能并非如此。
African-Americans under age 75 have over twice the risk of stroke death than whites in the United States. Regardless of race, stroke death is ~50% higher in the “Stroke Belt” and “Stroke Buckle” states of the Southeastern United States. We assessed geographic and racial differences in estimated 10-year stroke risk. The Reasons for Geographic and Racial Differences in Stroke study is a population-based cohort of men and women aged ≥45, recruited February 2003–September 2007 at this report, with oversampling of Stroke Belt / Buckle residents and African-Americans. Racial and regional differences in the Framingham Stroke Risk Score were studied in 23,940 participants without previous stroke or transient ischemic attack. The mean age, race and sex adjusted 10-year predicted stroke probability differed slightly across regions; 10.7% in the Belt, 10.4% in the Buckle, and 10.1% elsewhere (p <0.001). Geographic differences were largest for the score components of diabetes, and use of antihypertensive therapy. African-Americans had a higher age and sex-adjusted mean 10-year predicted stroke probability than whites; 11.3% versus 9.7%, respectively (p <0.001). Race differences were largest for the score components of hypertension, systolic blood pressure, diabetes, smoking, and left ventricular hypertrophy. While African-Americans had a higher predicted stroke probability than whites, regional differences were small. Results suggest that interventions to reduce racial disparities in stroke risk factors hold promise to reduce the racial disparity in stroke mortality. The same may not be true regarding geographic disparities in stroke mortality.
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影响因子：
8.3
作者：
Rosamond, WD;Folsom, AR;Shahar, E
通讯作者：
Shahar, E
影响因子：
120.7
作者：
Mokdad, AH;Ford, ES;Marks, JS
通讯作者：
Marks, JS
影响因子：
5.7
作者：
Kennedy, BS;Kasl, SV;Vaccarino, V
通讯作者：
Vaccarino, V
影响因子：
8.3
作者：
CASPER, ML;WING, S;POLLARD, RA
通讯作者：
POLLARD, RA
影响因子：
8.3
作者：
Howard, G;Prineas, R;Howard, V
通讯作者：
Howard, V