On the Computation of R(o) and Its Role on Global Stability
On the Computation of R(o) and Its Role on Global Stability
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DOI:
10.1007/978-1-4757-3667-0_13
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发表时间:
2001-02
期刊:
影响因子:
--
通讯作者:
C. Castillo-Chavez;Zhilan Feng;Wenzhang Huang
中科院分区:
文献类型:
--
作者:
C. Castillo-Chavez;Zhilan Feng;Wenzhang Huang
In this paper we outline the second generation operator approach developed by Diekmann and collaborators for the computation of the basic reproductive number, R 0. The use of this method is illustrated on epidemic models, mostly developed by the authors, that incorporate various degree of host and pathogen heterogeneity. Finally, conditions that clarify the connections between Ro and its relationship to the global asymptotic stability of the disease-free equilibrium are discussed.