Association between sum of volatile organic compounds and occurrence of building-related symptoms in humans: A study in real full-scale laboratory houses

Association between sum of volatile organic compounds and occurrence of building-related symptoms in humans: A study in real full-scale laboratory houses
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DOI:
10.1016/j.scitotenv.2020.141635
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发表时间:
2021-01-01
影响因子:
9.8
通讯作者:
Mori, Chisato
Mori, Chisato
中科院分区:
环境科学与生态学1区
文献类型:
--
作者:
Suzuki, Norimichi;Nakaoka, Hiroko;Mori, Chisato

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众所周知,室内环境,特别是室内空气质量(IAQ),对人类建筑相关症状(BRS)有显着影响,例如粘膜刺激、头痛和过敏,例如哮喘和特应性皮炎。 2017年,千叶大学启动了“Chemiless Town项目第三期”,旨在研究IAQ与人类健康的关系。大学校园内建有两栋实验室房屋(LH),其内部和外部相似,但室内空气挥发性有机化合物(VOC)水平不同。共有 141 名参与者使用他们的感官知觉评估了 IAQ。 VOC 水平差异与 BRS 发生率之间存在显着相关性(OR:6.89,95% CI:1.40-33.98)。研究表明,有过敏病史的人(OR:5.73,95%CI:1.12-29.32)和对化学物质高度敏感的人(OR:8.82,95%CI:1.16-67.16)容易经历BRS。因此,在建筑物建造时,有过敏史或对化学物质敏感的人可能是BRS的高危人群,因此关注室内空气质量以预防BRS非常重要。 (C) 2020 作者。由 Elsevier B.V. 出版
It is well known that the indoor environment, particularly indoor air quality (IAQ), has significant effects on building-related symptoms (BRSs) in humans, such as irritation ofmucosalmembranes, headaches, and allergies, such as asthma and atopic dermatitis. In 2017, Chiba University launched the "Chemiless Town Project Phase 3" to investigate the relationship between IAQ and human health. Two laboratory houses (LHs) were built on a university campus inwhich the interiors and exteriors were similar, but the levels of indoor air volatile organic compounds (VOCs) were different. A total of 141 participants evaluated IAQ using their sensory perception. There was a significant relationship between differences in VOC levels and BRSs occurrence (OR: 6.89, 95% CI: 1.40-33.98). It was suggested that people with a medical history of allergies (OR: 5.73, 95% CI: 1.12-29.32) and those with a high sensitivity to chemicals (OR: 8.82, 95% CI: 1.16-67.16) tended to experience BRSs. Thus, when buildings are constructed, people with a history of allergies or with a sensitivity to chemicals may be at high risk to BRSs, and it is important to pay attention to IAQ to prevent BRSs. (C) 2020 The Authors. Published by Elsevier B.V.