Synthesis and evaluation of a novel rhodamine B-based ‘off-on’ fluorescent chemosensor for the selective determination of Fe3+ ions
Synthesis and evaluation of a novel rhodamine B-based ‘off-on’ fluorescent chemosensor for the selective determination of Fe3+ ions
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DOI：
10.1016/j.snb.2016.09.163
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发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Jing Zhu
中科院分区：
文献类型：
--
作者：
Hailang Chen;Xiaofeng Bao;Hai Shu;Baojing Zhou;Renlong Ye;Jing Zhu
A new rhodamine B derivative, namely, N1-(benzo[d]thiazol-2-yl)-N4-(2-(3′,6′-bis (diethylamino)-3-oxospiro[isoindoline-1,9′-xanthen]-2-yl)ethyl)malea-mide (RDBSF), was designed, synthesized, and structurally characterized to develop a new chemosensor. UV–vis absorption and fluorescence spectroscopic studies show that RDBSF exhibits high sensitivity and selectivity toward Fe3+ in the presence of many other metal cations in a Tris-HCl solution (1 mM, pH = 7.4) containing 30% MeCN by forming a 1:1 complex with Fe3+. The binding association constant (Ka) of RDBSF for Fe3+ was estimated as 1.52 × 104 M−1 in the solution. The detection limit of Fe3+ by RDBSF was further determined as 11.6 nM. Intracellular imaging applications demonstrated that RDBSF can be used as a fluorescent probe for the detection of Fe3+ in HepG-2 cells.
