Rapid growth in infancy and childhood and obesity in later life - a systematic review
Rapid growth in infancy and childhood and obesity in later life - a systematic review
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DOI：
10.1111/j.1467-789x.2005.00183.x
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发表时间：
2005-05-01
期刊：
影响因子：
8.9
通讯作者：
Victora, CG
中科院分区：
文献类型：
--
作者：
Monteiro, POA;Victora, CG
肥胖与慢性病发病率之间的关系是众所周知的。本系统综述探讨了婴儿期和儿童期的快速生长作为生命后期超重和肥胖的可能决定因素的作用。我们回顾了MEDLINE关于婴儿期和儿童期生长的研究，以及儿童后期、青春期或成年期体重或肥胖的测量。论文的方法学质量使用唐斯和布莱克提出的标准进行评估。找到了符合评审标准的16篇文章。用于定义快速增长以及超重或肥胖的指标存在很大差异。测量体重或肥胖的年龄范围从3岁到70岁不等。尽管使用的定义有所不同，但13篇报道早期快速生长的文章发现，早期快速生长与后来的超重或肥胖存在显著关联。应努力规范快速生长的定义，以及儿童和青少年超重和肥胖的定义。在本综述中，最常见的快速增长定义是儿童时期两个不同年龄之间体重的z分数变化大于0.67。关于肥胖，国际肥胖工作组提出的定义似乎也是最合适的。目前的结果表明，早期生长确实与生命后期肥胖的流行有关。
The association between obesity and morbidity resulting from chronic diseases is well known. This systematic review addresses studies of the role of rapid growth in infancy and childhood as possible determinants of overweight and obesity laterin the life course. We reviewed MEDLINE for studies reporting on growth in infancy and childhood, as well as measures of weight or adiposity in later childhood, adolescence or adulthood. The methodological quality of the papers was assessed using the criteria suggested by Downs and Black. Sixteen articles that fulfilled review criteria were located. There was wide variability in the indicators used for defining rapid growth as well as overweight or obesity. The age range in which weight or adiposity was measured ranged from 3 to 70 years. In spite of differences in definitions used, 13 articles that reported on early rapid growth found significant associations with later overweight or adiposity. Efforts should be made to standardize the definition of rapid growth, as well as that of overweight and obesity in children and adolescents. The most frequent definition for rapid growth in this review was a Z-score change greater than 0.67 in weight for age between two different ages in childhood. Regarding obesity, the definition proposed by the International Obesity Task Force also appears to be most appropriate. The present results indicate that early growth is indeed associated with the prevalence of obesity later in the life course.