Phase-inversion tissue harmonic imaging compared with conventional B-mode ultrasound in the evaluation of pancreatic lesions

Phase-inversion tissue harmonic imaging compared with conventional B-mode ultrasound in the evaluation of pancreatic lesions
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DOI:
10.1007/s00330-003-2191-2
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发表时间:
2004-06-01
期刊:
影响因子:
5.9
通讯作者:
Guenther, RW
Guenther, RW
中科院分区:
医学2区
文献类型:
--
作者:
Hohl, C;Schmidt, T;Guenther, RW

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本研究的目的是比较传统 B 型超声 (BM) 和反相组织谐波成像 (PTHI) 在胰腺病理学方面的诊断灵敏度、特异性和图像质量。在一项前瞻性研究中,107 名年龄在 28 岁至 85 岁之间的患者按照随机选择的顺序接受了 BM 和 PTHI 胰腺超声检查。作为诊断参考,所有患者均进行上腹部增强 CT 或 MRI 检查。使用学生 t 检验评估敏感性和特异性。使用 Wilcoxon 符号秩检验和 Bowker 对称检验分析整体图像质量、病变明显性、液固分化和胰尾轮廓的差异。 107 名接受检查的患者中有 16 名 (15%) 未能诊断出来,并因腹部气体等技术限制而被排除。通过CT或MRI诊断出总共60个胰腺病变(囊肿、急性胰腺炎、胰管扩张、钙化和实体瘤)。对于检测胰腺病变,反相组织谐波成像的灵敏度比 BM(60%;40 中的 24)高出 70%(20 中的 14);然而,差异无统计学意义(p=0.46)。在评估病变时
The aim of this study was to compare the diagnostic sensitivity, specificity, and image quality of conventional B-mode US (BM) and phase-inversion tissue harmonic imaging (PTHI) regarding pancreatic pathology. In a prospective study, 107 patients, aged between 28 and 85 years, underwent US examinations of the pancreas with both BM and PTHI in a randomly chosen order. As diagnostic reference, either contrast-enhanced CT or MRI examinations of the upper abdomen were obtained in all patients. Sensitivity and specificity were evaluated using the Student's t test. Differences in overall image quality, lesion conspicuity, fluid-solid differentiation, and delineation of the pancreatic tail were analyzed using Wilcoxon's signed ranks test and Bowker's symmetry test. Sixteen of 107 examined patients (15%) were non-diagnostic and excluded due to technical limitations such as abdominal gas. A total of 60 pancreatic lesions (cysts, acute pancreatitis, dilatation of the pancreatic duct, calcifications, and solid tumors) were diagnosed by CT or MRI. Phase-inversion tissue harmonic imaging had a higher sensitivity of 70% (14 of 20) than BM (60%; 24 of 40) for the detection of pancreatic lesions; however, the difference was not statistically significant (p=0.46). In the assessment of lesions