EFFECTS OF INTRACELLULAR IONTOPHORETIC INJECTION OF CALCIUM AND SODIUM IONS ON LIGHT RESPONSE OF LIMULUS VENTRAL PHOTORECEPTORS
EFFECTS OF INTRACELLULAR IONTOPHORETIC INJECTION OF CALCIUM AND SODIUM IONS ON LIGHT RESPONSE OF LIMULUS VENTRAL PHOTORECEPTORS
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DOI：
10.1085/jgp.59.6.701
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发表时间：
1972-01-01
影响因子：
3.8
通讯作者：
BROWN, JE
中科院分区：
文献类型：
--
作者：
LISMAN, JE;BROWN, JE
当Ca ~（++）离子电泳注入鲎腹侧光感受器细胞时，光反应逐渐减弱。Ca++注入后，光响应的大小缓慢恢复。类似地，在细胞内注射Na+期间光响应逐渐减少，并且在注射停止后恢复。Na+注入过程中的减少率随着[Ca++]排出量的增加而增加。在含有0.1 mMCa++的溶液中，在Na+注射期间光响应的大小几乎没有进行性降低。细胞内注射Li+或K+不会逐渐降低光响应的大小。我们认为，[Na+] in的增加导致[Ca++] in的增加，[Ca++] in的增加无论如何都会导致对光反应性的降低。
During intracellular iontophoretic injection of Ca++intoLimulusventral photoreceptor cells, there is a progressive diminution of the light response. Following Ca++injection, the size of the light response slowly recovers. Similarly, there is a progressive diminution of the light response during intracellular injection of Na+and recovery after the injection is stopped. The rate of diminution during Na+injection is greater for higher [Ca++]out. In solutions which contain 0.1 mMCa++, there is nearly no progressive decrease in the size of the light response during Na+injection. Intracellular injections of Li+or K+do not progressively decrease the size of the light response. We propose that an increase in [Na+]inleads to an increase in [Ca++]inand that an increase in [Ca++]inby any means leads to a reduction in responsiveness to light.