On sympathetic vasoconstrictor tone in human skeletal muscle
On sympathetic vasoconstrictor tone in human skeletal muscle
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DOI：
10.1113/jphysiol.1943.sp004010
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发表时间：
1943-06-01
影响因子：
5.5
通讯作者：
Effron, AS
中科院分区：
文献类型：
--
作者：
Barcroft, H;Bonnar, WM;Effron, AS
用体积描记法测量了20-40岁正常男性前臂的血流量。手肘上阻断左前臂桡神经、正中神经和尺神经后，对右、左前臂进行了测量。4%普鲁卡因的1/50,000肾上腺素溶液将两条肢体浸入35 ℃的水中。发现阻塞臂中的血流约为。在控制中加倍。本文提出的证据表明，这种结果不是由于（1）左右前臂之间的自然差异，（2）皮肤循环中某些交感神经张力的意外释放，（3）骨骼肌张力的麻痹，（4）骨骼肌中肾上腺素血管扩张，（5）骨骼肌张力的增加，（6）骨骼肌张力的增加，（7）骨骼肌张力的增加，（8）骨骼肌张力的增加，（9）骨骼肌张力的增加，（10）骨骼肌张力的增加，（11）骨骼肌张力的增加，（12）骨骼肌张力的增加，（13）骨骼肌张力的增加，（14）骨骼肌张力的增加，（15）骨骼肌张力的增加，（16）骨骼肌张力的增加，（17）骨骼肌张力的增加，（18）骨骼肌张力的增加，（19）骨骼肌张力的增加，（（5）、释放动脉树中的张力和被动增加皮肤流量。结论：血管舒张主要是由于前臂肌肉中血管收缩纤维的麻痹，全身肌肉组织中交感神经张力的释放可使其血流量增加11/2升。分钟
Blood flow in the forearms of normal men aged 20-40 was measured plethysmographically. Measurements were made simultane-ously on the right and left forearm after the radial, median and ulnar nerves of the left arm had been blocked above the elbow by injn. of 4% procaine in 1/50,000 adrenaline. Both limbs were immersed in water at 35[degree]C. Blood flow in the blocked arm was found to be approx. double that in the control. Evidence is presented to show that the results are not due (1), to a natural difference between the right and left forearm; (2), to the accidental release of some sympathetic tone in the skin circulation; (3), to paralysis of tone in the skeletal muscle; (4), to adrenaline vasodilatation in the skeletal muscle; (5), to release of tone in the arterial tree and passive increase in skin flow. It is concluded that vasodilatation was mainly due to paralysis of vasoconstrictor fibers in the forearm muscle and that releasing sympathetic tone throughout the body musculature might increase its blood flow by 11/2 l./min.