Nutrition and bullous skin diseases
Nutrition and bullous skin diseases
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DOI：
10.1016/j.clindermatol.2010.03.036
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发表时间：
2010-11-01
影响因子：
2.7
通讯作者：
Grant-Kels, Jane M.
中科院分区：
文献类型：
--
作者：
Fedeles, Flavia;Murphy, Michael;Grant-Kels, Jane M.
自身免疫性和非自身免疫性大疱性疾病都可能与显著的发病率和死亡率有关。尽管我们对这些疾病的发病机制的了解大大增加，但关于影响其发病、病程和治疗的各种因素仍有许多需要了解。近年来，关于维生素、矿物质、和其他营养素对大疱性皮肤病的作用一些因素被认为是诱因(天疱疮中含有硫醇和苯酚的食物)，而其他因素被认为是保护性的(皮肤卟啉症中的抗氧化剂)。这篇文章回顾了文献中关于各种饮食因素在大疱性疾病中的作用的证据，包括非自身免疫性皮肤病和缺乏性皮肤病，需要进一步的研究和新的调查，以更好地了解饮食因素与大疱性疾病的具体联系，并更好地管理受这些疾病影响的患者(C)2010年由Elsevier Inc.出版
Autoimmune and nonautoimmune bullous diseases can both be associated with significant morbidity and mortality Although our understanding of the pathogenic mechanisms of these diseases has increased tremendously, there is still much to learn about the various factors affecting their onset, course, and therapy In recent years, increasing information has been published about the effect of vitamins, minerals, and other nutrients on bullous skin diseases Some factors are believed to be inducers (thiol and phenol-containing foods in pemphigus) whereas others are believed to be protective (antioxidants in cutaneous porphyrias) This contribution reviews the evidence in the literature of the role of various dietary factors in bullous diseases including the nonautoimmune and the deficiency dermatoses Additional studies and new investigations are needed to provide a better understanding of the specific associations of dietary factors with bullous diseases and better management for patients affected by these conditions (C) 2010 Published by Elsevier Inc