Effects of diesel exhaust on neurobehavioral and pulmonary functions
Effects of diesel exhaust on neurobehavioral and pulmonary functions
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DOI：
10.1080/00039890009603379
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发表时间：
2000-01-01
期刊：
影响因子：
--
通讯作者：
Kilburn, KH
中科院分区：
文献类型：
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作者：
Kilburn, KH
10名铁路工人和6名电工因呼吸急促而被转诊，他们也有反应迟钝、记忆丧失和睡眠障碍，所有这些都表明神经行为受损。假设是柴油机废气导致中枢神经系统损伤。六名电工在封闭的混凝土墙和屋顶内工作，这些墙和屋顶挡住了卡车排放的柴油废气。七名铁路机械师在室内调整了15-50年的柴油发动机，3名机组人员乘坐机车。神经行为和视觉功能的测量与26测试电池。与未暴露的男性相比，本研究中的16名受试者的反应时间、平衡、眨眼反射潜伏期R-1、文化公平、钉放置、线索制作和口头回忆显著受损。13名男性有异常视野，11名有异常的颜色混淆指数。9名男性出现气道阻塞。作者无法将异常归因于混杂因素或偏倚。严重的神经行为损害与暴露于密闭的柴油机废气有关。在对柴油暴露工人，特别是机车和卡车司机的其他研究中，研究人员应使用敏感的神经行为方法。
Ten railroad workers and 6 electricians referred for shortness of breath also had slowness of response, memory loss, and disordered sleep, all of which suggested neurobehavioral impairment. The hypothesis was that diesel exhaust causes central nervous system impairment. Six electricians worked within enclosed concrete walls and roofs that trapped diesel exhaust from trucks. Seven railroad mechanics had tuned diesel engines indoors for 15-50 y, and 3 crewmen rode in locomotives. Neurobehavioral and visual functions were measured with a 26-test battery. Compared with unexposed men, the 16 in this study had significantly impaired reaction time, balance, blink reflex latency R-1, Culture Fair, peg placement, trail making, and verbal recall. Thirteen men had abnormal visual fields, and 11 had abnormal color confusion indices. Nine men had airways obstruction. The author could not attribute abnormalities to confounding factors or bias. Severe neurobehavioral impairment was associated with exposure to confined diesel exhaust. In additional studies of diesel-exposed workers, especially drivers of locomotives and trucks, investigators should use sensitive neurobehavioral methods.