New antibacterial diterpenes from Pseudopterogorgia elisabethae
New antibacterial diterpenes from Pseudopterogorgia elisabethae
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DOI：
10.1002/hlca.200490099
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发表时间：
2004-01-01
影响因子：
1.8
通讯作者：
Jayatilake, GS
中科院分区：
文献类型：
--
作者：
Ata, A;Win, HY;Jayatilake, GS
从采集自巴哈马群岛的香豆杉的甲醇提取物中分离得到4个新的二萜化合物，分别为香豆素E(1)、香豆素F(2)、香豆素P(3)和香豆素Q(4)，并通过波谱分析确定了它们的结构。化合物3和4对革兰氏阳性菌化脓性链球菌、金黄色葡萄球菌和粪肠球菌具有选择性的抗菌活性。
From the MeOH extract of Pseudopterogorgia elisabethae, collected from the Bahamas, four new diterpenes, elisabethin E (1), elisabethin F (2), pseudopterosin P (3), and pseudopterosin Q (4), were isolated and their structures established with the aid of extensive spectroscopic studies. Compounds 3 and 4 showed antibacterial activity selectively against the Gram-positive bacteria Streptococcus pyogenes, Staphylococcus aureus, and Enterococcus faecalis.