One-Year Results of the Think Health! Study of Weight Management in Primary Care Practices
One-Year Results of the Think Health! Study of Weight Management in Primary Care Practices
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DOI：
10.1038/oby.2011.329
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发表时间：
2012-06-01
期刊：
影响因子：
6.9
通讯作者：
Wadden, Thomas A.
中科院分区：
文献类型：
--
作者：
Kumanyika, Shiriki K.;Fassbender, Jennifer E.;Wadden, Thomas A.
思考健康！这项研究评估了一项行为减肥计划，该计划改编自糖尿病预防计划(DPP)的生活方式干预，以帮助初级保健提供者(PCP)和充当生活方式教练(LC)的辅助工作人员为他们的患者提供减肥咨询。在一项在5个临床站点进行的随机试验中，研究参与者在每个站点内以1：1的比例被随机分配到“基本+”组(n=137)或“基本”组(n=124)。“基本+”组每4个月提供一次PCP咨询，并在第一年期间每月去LC就诊，而“基本”组每4个月只提供一次PCP咨询。参与者主要是女性(84%)，65%的非裔美国人，16%的西班牙裔美国人和19%的白人。在每组接受12个月体重测量的72%的参与者中，基础+组1年体重变化(Kg)的平均值(95%CI)为-1.61(-2.68，-0.53)，基础+组为-0.62(-1.45，0.20)(差值：0.98(-0.36，2.33)；P=0.15)。在使用随机参与者的所有可用体重数据的基于模型的估计中，结果相似，并对潜在的混杂因素进行了调整。更多的基本+(22.5%)比基本(10.2%)的参与者减去了基线体重的5%(P=0.022)。在一项描述性的非随机分析中，也考虑了不完全的就诊次数，参加LC就诊的Basic Plus参与者的平均体重变化为-3.3公斤，而参加LC就诊的参与者的平均体重变化为+0.53公斤
The Think Health! study evaluated a behavioral weight loss program adapted from the Diabetes Prevention Program (DPP) lifestyle intervention to assist primary care providers (PCPs) and auxiliary staff acting as lifestyle coaches (LCs) in offering weight loss counseling to their patients. In a randomized trial conducted at five clinical sites, study participants were randomly assigned in a 1:1 ratio within each site to either "Basic Plus" (n = 137), which offered PCP counseling every 4 months plus monthly LC visits during the first year of treatment, or "Basic" (n = 124), which offered only PCP counseling every 4 months. Participants were primarily (84%) female, 65% African American, 16% Hispanic American, and 19% white. In the 72% of participants in each treatment group with a 12-month weight measurement, mean (95% CI) 1-year weight changes (kg) were -1.61 (-2.68, -0.53) in Basic Plus and -0.62 (-1.45, 0.20) in Basic (difference: 0.98 (-0.36, 2.33); P = 0.15). Results were similar in model-based estimates using all available weight data for randomized participants, adjusting for potential confounders. More Basic Plus (22.5%) than Basic (10.2%) participants lost >= 5% of their baseline weight (P = 0.022). In a descriptive, nonrandomized analysis that also considered incomplete visit attendance, mean weight change was -3.3 kg in Basic Plus participants who attended LC visits vs. + 0.53 kg in those attending