Neglected tropical diseases
Neglected tropical diseases
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DOI：
10.1093/bmb/ldp046
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发表时间：
2010-03-01
影响因子：
6.7
通讯作者：
Solomon, Anthony W.
中科院分区：
文献类型：
--
作者：
Feasey, Nick;Wansbrough-Jones, Mark;Solomon, Anthony W.
被忽视的热带病是主要影响世界上最贫穷人口的传染病。几十年来，由于对发展中国家的普遍忽视，以及最近对艾滋病、结核病和疟疾的高度关注，它们一直被忽视。通过检索PubMed和我们现有的馆藏，我们选择了主要的研究和综述文章。麦地那龙线虫病即将被根除。麻风病和盘尾丝虫病正在减少。有雄心勃勃的计划，以消除沙眼和淋巴丝虫病。虽然有行之有效的策略来控制几种NTD，但这些疾病继续造成巨大的发病负担。迫切需要进行更多的基础和业务研究、药物和疫苗开发，以及各国政府和国际机构更优先考虑这些问题。
The neglected tropical diseases (NTDs) are infectious diseases that principally impact the world's poorest people. They have been neglected for decades, initially as part of a general disregard for the developing world, and more recently due to the intensity of focus on HIV/AIDS, tuberculosis and malaria.Primary research and review articles were selected for inclusion using searches of PubMed and our existing collections.There have been recent notable successes in NTD control. Dracunculiasis is approaching eradication. Leprosy and onchocerciasis are in decline. There are ambitious plans to eliminate trachoma and lymphatic filariasis. Investment in NTD control has high rates of economic return.Although there are proven strategies to control several NTDs, these diseases continue to cause a massive burden of morbidity. There is urgent need for more basic and operational research, drug and vaccine development, and greater prioritization by governments and international agencies.