Pharmacologic modification of serotonergic function: drugs for the study and treatment of psychiatric and other disorders.

Pharmacologic modification of serotonergic function: drugs for the study and treatment of psychiatric and other disorders.
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血清素能功能的药理学修饰:用于研究和治疗精神疾病和其他疾病的药物。

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发表时间:
1986
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通讯作者:
Fuller Rw
Fuller Rw
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作者:
Fuller Rw

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:直接血清素激动剂、选择性血清素摄取抑制剂、血清素受体拮抗剂和其他影响血清素能功能的药物的开发有助于研究实验动物脑血清素神经元的生理功能以及血清素受体亚型的识别和分类。这些类型的药剂是用于治疗精神疾病(例如抑郁症)和其他疾病(例如暴饮暴食、酗酒、肌阵挛和慢性疼痛)的真实或潜在药物。此外,这些药物还可以评估人类大脑血清素受体的功能状态。
: The development of direct serotonin agonists, selective inhibitors of serotonin uptake, serotonin receptor antagonists, and other drugs affecting serotonergic function has aided the study of physiologic functions of brain serotonin neurons in laboratory animals and the recognition and classification of serotonin receptor subtypes. Agents of these types are real or potential drugs for the treatment of psychiatric disorders (e.g., depression) and other disorders such as overeating, alcoholism, myoclonus, and chronic pain. In addition, the agents may permit assessment of the functional state of brain serotonin receptors in humans.