Birth cohort differences in the use of medications in a Brazilian population of older elderly: the Bambuí cohort study of aging (1997 and 2008)
Birth cohort differences in the use of medications in a Brazilian population of older elderly: the Bambuí cohort study of aging (1997 and 2008)
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DOI：
10.1590/s0102-311x2011001500014
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发表时间：
2011-01-01
期刊：
影响因子：
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通讯作者：
Lima-Costa, Maria Fernanda
中科院分区：
文献类型：
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作者：
Loyola Filho, Antônio Ignácio de;Firmo, Josélia O. A.;Lima-Costa, Maria Fernanda
本研究在巴西米纳斯吉拉斯州班布伊的一项基于人群的队列研究中，对两个出生队列（1916 - 1926年和1927 - 1937年出生）中老年人的药物使用差异进行了研究。该研究使用了1997年基线调查（n = 492）和2008年第11波调查（n = 620）中71-81岁参与者的数据。与早期队列相比，最近队列中目前使用的药物数量（平均值分别为4.6和3.4）和多种药物的患病率（分别为46.6%和29.1%）更高。这些差异与性别、年龄、学校教育、过去12个月内的就医次数以及慢性病的数量无关。最近的队列显示，精神活性药物、调脂药物、糖尿病药物和抗血栓药物的使用存在显著差异，动脉高血压药物的使用也发生了变化。一般来说，e变化与高收入国家老年人口中观察到的变化一致。
This study examined differences in the use of medications in two birth cohorts (born from 1916 to 1926 and from 1927 to 1937) among older elderly in the population-based cohort study in Bambui, Minas Gerais State, Brazil. The study used data on participants who were 71-81 years of age in the baseline survey in 1997 (n = 492) and in the 11th wave, in 2008 (n = 620). The number of medications currently consumed (mean = 4.6 and 3.4, respectively) and prevalence of polypharmacy (46.6% and 29.1%, respectively) were higher in the more recent cohort as compared to the earlier one. These differences were independent of gender, age, schooling, number of medical visits in the previous 12 months, and number of chronic conditions. The more recent cohort showed significant differences in the use of psychoactive drugs, lipid modifying agents, drugs for diabetes, and antithrombotic agents, as well as changes in drugs used for arterial hypertension. In general, the.;e changes are consistent with those observed in elderly populations in high-income countries.