Identification of ORF636 in Phage φSLT Carrying Panton-Valentine Leukocidin Genes, Acting as an Adhesion Protein for a Poly(Glycerophosphate) Chain of Lipoteichoic Acid on the Cell Surface of Staphylococcus aureus
Identification of ORF636 in Phage φSLT Carrying Panton-Valentine Leukocidin Genes, Acting as an Adhesion Protein for a Poly(Glycerophosphate) Chain of Lipoteichoic Acid on the Cell Surface of Staphylococcus aureus
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DOI：
10.1128/jb.01793-08
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发表时间：
2009-07-15
影响因子：
3.2
通讯作者：
Kamio, Yoshiyuki
中科院分区：
文献类型：
--
作者：
Kaneko, Jun;Narita-Yamada, Sachiko;Kamio, Yoshiyuki
金黄色葡萄球菌的温和噬菌体携带Panton-Valentine杀白细胞素基因。在这里，我们确定ORF 636，噬菌体尾尖结构的组成部分，作为一个识别/粘附蛋白的聚（甘油磷酸）链脂磷壁酸的细胞表面上的S。金黄色。ORF 636与S.金黄色葡萄球菌;它不结合任何其他葡萄球菌物种或几种革兰氏阳性细菌。
The temperate phage phi SLT of Staphylococcus aureus carries genes for Panton-Valentine leukocidin. Here, we identify ORF636, a constituent of the phage tail tip structure, as a recognition/adhesion protein for a poly(glycerophosphate) chain of lipoteichoic acid on the cell surface of S. aureus. ORF636 bound specifically to S. aureus; it did not bind to any other staphylococcal species or to several gram-positive bacteria.