BONE STATUS AND FRACTURE RATES IN 2 REGIONS OF YUGOSLAVIA
BONE STATUS AND FRACTURE RATES IN 2 REGIONS OF YUGOSLAVIA
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DOI：
10.1093/ajcn/32.3.540
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发表时间：
1979-01-01
影响因子：
7.1
通讯作者：
NORDIN, BEC
中科院分区：
文献类型：
--
作者：
MATKOVIC, V;KOSTIAL, K;NORDIN, BEC
在两个饮食习惯非常不同的南斯拉夫人群中评估骨状况和骨折率。在A区（Podragon），每日钙摄入量约为B区（Istra）的两倍。其他营养素的摄入量相似但差异较小。在区域B掌骨皮质宽度减少，在所有年龄组的男女，但差异往往随着年龄的增长而减少。B区股骨近端骨折发生率高于A区，但两区前臂骨折发生率无差异。任何年龄的骨量显然是年龄和性别的结果，很可能是其他遗传因素决定的，但也表明这种表达与营养有关。这些数据表明，营养（特别是钙的摄入量）是年轻人骨量的重要决定因素，但似乎对男性或女性与年龄相关的骨质流失影响不大。老年人皮质骨量的主要决定因素似乎是中年时的皮质骨量。老年人股骨近端骨折反映了皮质骨质量的下降，而中年妇女前臂远端骨折与皮质骨质量或营养状况无关。
Bone status and fracture rates were evaluated in two Yugoslavia populations with very different dietary habits. In district A (Podravina) the daily Ca intake was about twice that in district B (Istra). There were similar but smaller differences in the intakes of other nutrients. In district B metacarpal cortical width was reduced in all age groups of both sexes but the difference tended to decrease with age. The proximal femur fracture rate was higher in district B than district A but there was no difference between the forearm fracture rates in the 2 districts. Bone mass at any age is clearly the result of age and sex and most probably other genetically determined factors but also show that this expression is nutrition related. The data suggest that nutrition (in particular the Ca intake) is an important determinant of bone mass in young adults but seems to have little effect on age-related bone loss in either males or females. The main determinant of cortical bone mass in the elderly seems the cortical bone mass in middle life. The proximal femur fractures of old people reflect declining cortical bone mass but the distal forearm fractures of middle aged women are unrelated to cortical bone mass or nutritional status.