Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae.
Rhino-Orbital Mucormycosis in a COVID-19 Patient Co-Infected With Klebsiella Pneumoniae.
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DOI：
10.7759/cureus.17249
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发表时间：
2021-08
期刊：
影响因子：
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通讯作者：
Khurana S
中科院分区：
文献类型：
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作者：
Wadhwa L;Khurana S
我们报告一例34岁男性，患有2019冠状病毒病（COVID-19），血糖不受控制，伴右眼眶蜂窝织炎和右筛窦和上颌窦炎。通过诊断性鼻内窥镜（DNE）收集的中鼻道组织活检的组织学显示存在毛霉菌和肺炎克雷伯菌（K。肺炎）。在静脉（IV）胰岛素、头孢哌酮-舒巴坦和泊沙康唑（由于无法获得阿替霉素B）给药后，患者接受了外科清创术和功能性鼻内镜手术（FESS）。在术后两周接受抗生素和抗真菌药物治疗后，患者的预后良好，进一步的检查显示血细胞计数和炎症标志物有所改善。
We present a case of a 34-year-old male with coronavirus disease 2019 (COVID-19) and uncontrolled blood sugar with right orbital cellulitis and right ethmoidal and maxillary sinusitis. Histopathology of a middle meatus tissue biopsy collected via diagnostic nasal endoscopy (DNE) revealed the presence of Mucor and Klebsiella pneumoniae (K. pneumoniae). After the administration of intravenous (IV) insulin, cefoperazone-sulbactam, and posaconazole (due to the non-availability of amphotericin B), he underwent surgical debridement and functional endoscopic sinus surgery (FESS). After being on antibiotics and antifungals for two weeks post-surgery, the patient had a favorable outcome and further tests revealed improved blood counts and inflammatory markers.